Preparation of monodisperse multilayer vesicles of controlled size and high encapsulation ratio.

(Received 11 September 1992, accepted 5 November 1992)

Abstract
The effect of shear on lyotropic lamellar phases is studied by light scattering and microscopic observations. We found that in a certain range of shear rate the lamellar phase organizes itself into spherical multilayer vesicles of well controlled size. The size is shown to vary as the inverse of the square root of the shear rate. A simple explanation in terms of a balance between shear stress and elastic forces is given.